Recently, Prof. Zhou’s research group in our institute cooperated with researchers from well-known universities in the United Kingdom and the Netherlands to publish a review titled "High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology" in the top journal "Chemical Reviews" (impact factor 52.758) Paper (DOI: org/10.1021/acs.chemrev.0c00752), and was selected as the cover of the journal. Qingdao University is the first unit and correspondent of the article, and Professor Zhou Qihui is the first corresponding author. The complex interaction between cells and biomaterials is very important in the research of tissue engineering and regenerative medicine. However, it is not possible to efficiently screen the properties of biomaterials using traditional strategies, so it is difficult to obtain the optimal cellular response. Professor Zhou Qihui uses high-throughput screening strategies to explore the complex interactions between cells and biological materials to provide an optimal microenvironment for tissue repair and regeneration. In the review, Professor Zhou introduced in depth the 2D/3D high-throughput screening platform (gradient and microarray structure), biomaterial transcriptomics, high-content imaging, computational simulation, medical transformation, and the challenges and future prospects in this field. This article is of great significance for clarifying the relationship between materials and biological behavior, accelerating the development of high-performance biomaterials and translational medicine applications. The Institute of Translational Medicine encourages young talents to carry out interdisciplinary innovative research, and has achieved a series of high-level research results in recent years. Professor Zhou Qihui’s team focuses on cell and molecular biology, clinical medicine, tissue engineering and regenerative medicine, chemistry, materials science and other disciplines, focusing on basic and applied research on the interaction between biomaterials and (stem) cells, tissue repair and regeneration . This work was funded by the National Natural Science Foundation of China, the Natural Science Foundation of Shandong Province, and the Shandong Provincial Colleges and Universities "Young Creative Science and Technology Project" team.

Article link: https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.0c00752