Shan Chan

Assistant Professor

Email: shanchan@qdu.edu.cn; shanchan@mail2.sysu.edu.cn

Office: Room 816

http:/info/2015/1180.htm

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Education

Ph. D, Sun Yat-sen University, 2016

B.S., Lanzhou Universiy, 2011

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Research interests

The structure and function of non-coding DNAs and RNAs

The regulation of cancer cell fate

Evaluation of antitumor activity of small molecule compounds

v Selected Publications

(1) Chan Shan*, Xinzhe Chen, Hongjing Cai, Jing Li, Yinfeng Zhang, Jinning Gao, Zhixia Zhou, Xinmin Li, Cuiyun Liu, Peifeng Li, Kun Wang*. The Emerging Roles of Autophagy-Related MicroRNAs in Cancer. International Journal of Biological Sciences. 2021.

(2) Chan Shan*, Yinfeng Zhang, Xiaodan Hao, Jinning Gao, Xinzhe Chen, Kun Wang*. Biogenesis, functions and clinical significance of circRNAs in gastric cancer. Molecular Cancer. 2019.

(3) Chan Shan#, Jinwu Yan#, Yuqing Wang, Tong Che, Zhouli Huang, Aichun Chen, Peifen Yao, Jiaheng Tan, Ding Li, Tianmiao Ou*, Lianquan Gu, Zhishu Huang*. Design, synthesis, and evaluation of isaindigotone derivatives to downregulate c-myc transcription via disrupting the interaction of NM23-H2 with G-quadruplex. Journal of Medicinal Chemistry. 2017.

(4) Chan Shan#, Jing Lin#, Jinqiang Hou, Huiyun Liu, Shuobin Chen, Aichun Chen, Tianmiao Ou*, Jiaheng Tan, Ding Li, Lianquan Gu, Zhishu Huang*. Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule. Nucleic Acids Research. 2015.

(5) Chan Shan, Jiaheng Tan, Tianmiao Ou, Zhishu Huang*. Natural products and their derivatives as G-quadruplex binding ligands. Science China Chemistry. 2013.