Hua Zhang （Prof. PhD Advisor）
Director of Shandong Key Laboratory of Chemical Biology of Natural Medicines
School of Biological Science and Technology, University of Jinan
336, West Nan Xinzhuang Road, Jinan 250022
Email: bio_zhangh@ujn.edu.cn
Tel.:0531-89736199
Homepage: http://npmc.ujn.edu.cn/
Education
2001.09 – 2006.06 PhD in Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1997.09 – 2001.06 BSc in Chemistry, College of Chemistry, Shandong University
Academic career
2015.09 – Now Prof. (Leading scientist), University of Jinan
2014.01 – 2015.08 Professorial research fellow, Shanghai Institute of Materia Medica
2011.08 – 2013.12 A/Professorial research fellow, Shanghai Institute of Materia Medica
2006.08 – 2010.12 Post-doc, The University of Queensland, Australia
Research field
Natural products and Medicinal chemistry: Discovery of bioactive constituents from natural resources; Synthesis and structural modification of small-molecule natural products; Rational design and synthesis of bioactive compounds mainly targeting epigenetics.
Five-year research funding
1、 National Natural Science Foundation of China (General project, 82073729), ¥550,000, 2021.01–2024.12.
2、 Innovation Team Project of Jinan Science & Technology Bureau (2018GXRC003), ¥1,500,000, 2019.01–2021.12.
3、 Natural Science Foundation of Shandong Province (Key fundamental project, ZR2018ZC0944), ¥375,000, 2018.06–2020.12.
4、 Natural Science Foundation of Shandong Province for Distinguished Young Scholar (JQ201721, ¥600,000, 2017.08–2020.08.
5、 The Young Taishan Scholars Project (tsqn20161037), ¥500,000, 2017.01–2021.12.
6、 Shandong Talents Team Cultivation Plan of University Preponderant Discipline (No.10027), 6,000,000, 2016.01–2020.12.
Honors and Rewards
Excellent teacher reward of University of Jinan (2016)
2nd class Prize of National Natural Science (4/5, 2013)
Excellent young researcher reward of SIMM (2013)
Top honors student reward of CAS (2006)
Procter & Gamble excellent PhD student reward (2006)
Excellent PhD graduate of Shanghai city (2006)
Three-year representative publications
1. Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer, Cancer Research, 2021, 81(15), 4027-4040. (In collaboration with Qingdao University, IF 12.701)
2. Bioactive sesquiterpenoids from the flower buds of Tussilago farfara, Bioorganic Chemistry, 2021, 107, 104632. (IF 5.275)
3. Bioactive terpenoid constituents from Eclipta prostrata, Phytochemistry, 2020, 170, 112192. (IF 4.072)
4. Direct oxidative dearomatization of indoles: access to structurally diverse 2,2-disubstituted indolin-3-ones, Chemical communications, 2019, 55, 6535-6538. (IF 6.222)
5. An updated overview on the development of new photosensitizers for anticancer photodynamic therapy, Acta Pharmaceutica Sinica B, 2018, 8(2), 137–146. (IF 11.431)
Academic service
Member of editorial board for Acta Pharmaceutica Sinica B
Council member of Shandong Pharmaceutical Society
Expert reviewer of National Natural Science Foundation of China
Peer reviewer for 20+ international journals
