Zhang Dejiu
Research Background
The mechanism of translation initiation
Education Background
2003.09 -2007.07, College of life sciences, Northwest A&F University, B. S.
2007.09 -2010.07, College of life sciences, Lanzhou University, M.S.
2010.09 -2016.07, Institute of Biophysics, Chinese Academy of Sciences, PhD
Work Experience
2016.07-2019. 07, Assistant Professor, Institute of Biophysics, CAS
2019.08-Present, Assistant Professor, Qingdao University
Selected publication
1. Gao, Y., Bai, X., Zhang, D.J., Han, C., Yuan, J., Liu, W., Cao, X., Chen, Z., Shangguan, F., Zhu, Z., et al. (2016). Mammalian elongation factor 4 regulates mitochondrial translation essential for spermatogenesis. Nature structural & molecular biology 23(5): 441-449..
2. Zhang, D.J., Yan, K., Liu, G., Song, G., Luo, J., Shi, Y., Cheng, E., Wu, S., Jiang, T., Lou, J., et al. (2016). EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome. Nature structural & molecular biology 23, 125-131.
3. Zhang, D.J., Yan, K., Zhang, Y., Liu, G., Cao, X., Song, G., Xie, Q., Gao, N., and Qin, Y. (2015). New insights into the enzymatic role of EF-G in ribosome recycling. Nucleic acids research 43, 10525-10533.
4. Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D.J., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., et al. (2015). HflX is a ribosome-splitting factor rescuing stalled ribosomes under stress conditions. Nature structural & molecular biology 22, 906-913.
5. Liu, G., Song, G., Zhang, D., Zhang, D.J., Li, Z., Lyu, Z., Dong, J., Achenbach, J., Gong, W., Zhao, X.S., et al. (2014). EF-G catalyzes tRNA translocation by disrupting interactions between decoding center and codon-anticodon duplex. Nature structural & molecular biology 21, 817-824.
