Name: ZHANG Yuan
Subject: Neurobiology
Tel/Fax: +86-532-82991791
Email: yuan_zhang84@aliyun.com
Address: Dengzhou Road, Institute for Translational Medicine, The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao 266021, China
Resume:
ZHNAG Yuan, Ph.D., graduated from school of life science, Jilin University in 2014. In 2015, she joined the Institute for Translational Medicine, Qingdao University. In 2020, she was selected into the project “Youth Outstanding Talents of Qingdao University”. Dr. Zhang research interests cover protein function regulation and nerve damage and repair, mainly for the prevention and treatment of Alzheimer's disease using immunotherapy and small molecule antibody drugs. She is currently engaged in research on the mechanism and treatment of neurological diseases, as well as the regulation mechanism of non-coding RNA. She presided over National Natural Science Foundation of China, Shandong Natural Science Foundation Project, Qingdao Basic Research Project, and Chinese Postdoctoral Project. She has published more than 10 SCI articles with a cumulative impact factor of IF>40; applied for 3 national invention patents.
Selected Publications:
1. Yuan Zhang*, Lili Qian, Yingying Liu, Ying Liu, Wanpeng Yu, Yanfang Zhao.CircRNA-ceRNA Network Revealing the Potential Regulatory Roles of CircRNA in Alzheimer's Disease Involved the cGMP-PKG Signal Pathway.Front Mol Neurosci. 2021, 14:665788.
2. Yuan Zhang*, Yanfang Zhao, Xiang Ao, Wanpeng Yu, Lei Zhang, Yu Wang, Wenguang Chang. The Role of Non-coding RNAs in Alzheimer's Disease: From Regulated Mechanism to Therapeutic Targets and Diagnostic Biomarkers. Front Aging Neurosci. 2021, 13:654978.
3. Yuan Zhang*, Yanfang Zhao, Ying Liu, Man Wang, Wanpeng Yu, Lei Zhang. Exploring the regulatory roles of circular RNAs in Alzheimer's disease. Transl Neurodegener. 2020,9(1):35.
4. Yuan Zhang*, Lei Zhang, Yu Wang, Han Ding, Sheng Xue, Hongzhao Qi, Peifeng Li *. MicroRNAs or Long Noncoding RNAs in Diagnosis and Prognosis of Coronary Artery Disease. Aging and Disease. 2019, 10(2):353-366.
5. Yuan Zhang*, Lei Zhang, Yu Wang, Han Ding, Sheng Xue, Hua Yu, Longgang Hu, Hongzhao Qi, Yin Wang, Wenjie Zhu, Dacheng Liu, Peifeng Li*. KCNQ1OT1, HIF1A-AS2 and APOA1-AS are promising novel biomarkers for diagnosis of coronary artery disease. Clinical and experimental pharmacology and physiology. 2019, 46(7):635-642.
6. Yuan Zhang*#, Xu Chen#, Yanfang Zhao, Murugavel Ponnusamy, Ying Liu. The role of ubiquitin proteasomal system and autophagy-lysosome pathway in Alzheimer's disease. Rev Neurosci. 2017, 28(8):861-868.
7. Yuan Zhang, Xu Chen, Jinyu Liu, Yingjiu Zhang*. The protective effects and underlying mechanism of an anti-oligomeric Aβ42 single-chain variable fragment antibody. Neuropharmacology. 2015, 99:387-95.
8. Yuan Zhang, Yuanhong Sun, Yangyang Huai, YingJiu Zhang*. Functional Characteristics and Molecular Mechanism of a New scFv Antibody Against Aβ42 Oligomers and Immature Protofibrils. Mol Neurobiol. 2015, 52(3):1269-1281.
