Population aging is a serious problem facing China today. According to the United Nations, the country's population over 65 years old will reach 167 million by 2020, accounting for about a quarter of the world's total aging population. The study of aging and anti-aging mechanisms has become an important topic in response to the aging of the population. According to the current research results, the anti-aging effect is mainly manifested through three aspects: calorie restriction, mitochondrial hypo-promotion, and autophagy.

With the help of the third-generation gene sequencing platform, proteomics platform, and targeted drug screening platform of the Translational Medical College, the following key research projects based on the above three anti-aging effects will be carried out:

1. The effect of gene epigenetic modification and genetic imprinting on the aging and lifespan of organisms

2. Exploring aging and lifespan-related genes and signal pathways through genomics big data combined with proteomics research

3. Exploring key regulatory genes and therapeutic targets for aging-related diseases, such as Alzheimer's disease, Parkinson's disease, and other diseases

4. According to the key target proteins screened out, carrying out the screening and development of potential anti-aging drugs

Center director: Dr. Sujie Zhu

Phone: 053282991791

email: zhusujie@bjmu.edu.cn