Name: MIN ZHU
Subject: Genetics and Cell Biology
Tel: 0532-82991791
Email: minzhu@qdu.edu.cn
Address: Institute of Translational Medicine, The Affiliated Hospital of Qingdao University, College of Medicine, Qingdao University, No. 38 Dengzhou Road, Qingdao, 266071, Shandong, China
Resume:
MIN ZHU, Ph.D., is an associate professor in Institute of Translational Medicine, Qingdao University. Zhu’s research uses mammalian cells and the fission yeast Schizosaccharomyces pombe as model systems to uncover respects of DNA damage response, relationship of DNA repair and genome instability. She obtained her postdoc training in City of Hope and The Scripps Research Institute. She has been awarded Best poster award in 5th International Symposium on DNA Damage Response & Human Disease (2014), 5th International Conference on Biomedical and Environmental Science & Technologies (icBEST-2014); Best poster award in 6th International Symposium on DNA Damage Response @ Human Disease (2015).
Research Interests:
Prof. Zhu’s research interests cover DNA damage response and genome instability
Selected Publications:
1. Hongchang Zhao†, Zhifeng Wang†, Min Zhu†, Ji Liao & Xingzhi Xu*. USP11 suppresses CHK1 activation by deubiquitinating CLASPIN.Genome Instability & Disease (2021) 2:184–194 https://doi.org/10.1007/s42764-021-00034-1 (Co-first author)
2. Zhifeng Wang, Yamin Gong, Bin Peng, Ruifeng Shi, Dan Fan, Hongchang Zhao, Min Zhu, Haoxing Zhang, Zhenkun Lou, Jianwei Zhou, Wei-Guo Zhu, Yu-Sheng Cong, Xingzhi Xu. MRE11 UFMylation promotes ATM activation. Nucleic Acids Res. 2019 Feb 20. pii: gkz110. doi: 10.1093/nar/gkz110.
3. Min Zhu†, Hongchang Zhao†, Oliver Limbo, and Paul Russell*. Mre11 complex links sister chromatids to promote repair of a collapsed replication fork. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):8793-8798. doi: 1073/pnas.1808189115
4. Hongchang Zhao†, Min Zhu†, Oliver Limbo & Paul Russell*. RNase H eliminates R-loops that disrupt DNA replication but is nonessential for efficient DSB repair. Embo reports. 2018. doi: 10.15252/embr.201745335
5. Min Zhu†, Hongchang Zhao†, Ji Liao, and Xingzhi Xu*. HERC2/USP20 coordinatesCHK1 activation by modulating CLASPIN stability. Nucleic Acids Research, doi: 10.1093/nar/gku978 October 17, 2014
6. Hongchang Zhao†, Min Zhu†, Gelin Dou, Hongli Zhao, Bingtao Zhu, Jing Li, Ji Liao,Xingzhi Xu*. 2014. BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNAdamage response. Cell Cycle 13(11), 1777-87.
