Proteins are the essential building blocks of life and are closely related to the biological processes of organisms and the occurrence and development of diseases. The term “proteome” refers to the entire set of proteins expressed and modified by a cell, tissue, or organism. Proteomics is the systematic, large-scale analysis of the expression, localization, modification, interaction, and dynamics of proteins in organisms under certain physiological and pathological conditions, which helps us understand the laws of life, explain the mechanisms of diseases, and find biomarkers and drug targets for disease diagnosis and treatment.
Current proteomics research, which is based on high-throughput liquid-mass spectrometry, has become an important part of modern biology and medical research. Equipped with the Thermo Fisher EASY-nLC1200 HPLC and Q-Exactive mass spectrometer, the proteomics research center aims to bring state-of-the-art mass spectrometry and proteomics technologies to the basic and translational research of biology and biomedicine. The main research directions of our center include the following:
1. Neuronal synaptic signaling network in neurodevelopment;
2. Synaptic signaling in the proliferation and metastasis of brain tumors;
3. Identification of biomarkers for the diagnosis and treatment of prostate cancer.
Director: Li Jing
Tel: 0532-82991791
Email: jingli@qdu.edu.cn