Research Progress
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Professor Qihui Zhou from our institute published a cover review paper in 《Chemical Reviews》
Recently, Prof. Zhou’s research group in our institute cooperated with researchers from well-known universities in the United Kingdom and the Netherlands to publish a review titled "High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology" in the top journal "Chemical Reviews" (impact factor 52.758) Paper (DOI: org/10.1021/acs.chemrev.0c00752), and was selected as ...
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Significant progress reported in Nature Cell Biology! Professor Wang Kun's team at our Institute reveals the molecular mechanism of piRNA in regulating cardiac hypertrophy.
Recently, Professor Kun Wang’s team at our Institute published their research results in “The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA” online in Nature Cell Biology (IF=20.042). Qingdao University was the first author of one part, Professor Wang Kun was the corresponding author, and PhD student Gao Xiangqian was...
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The research results of Dr. Hongzhao Qi at our Institute were published in Theranostics.
In recent years, the use of exosomes as a targeted drug delivery vehicle has received increasing attention. However, the existing sources of exosomes have several problems, such as low safety and difficulty in large-scale production, and their clinical transformation is difficult. Recently, Dr. Hongzhao Qi at our Institute published a paper in Theranostics, which reported the use of the pH resp...
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Our research team reported a novel biosensor for miRNA diagnosis in Nanoscale.
Noncoding small RNAs, such as microRNAs, have become biomarkers for many diseases in clinical diagnosis. The dysregulation of these microRNAs may be related to many different diseases, such as cancer, dementia, and cardiovascular diseases. The key to the effective treatment of these diseases is early and accurate preliminary diagnosis, which can improve the patient’s chances of survival.Our te...
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A research group at our institution published their findings on the new mechanism of lncRNA regulating myocardial infarction in Nature Communications.
Recently, Professor Wang Kun’s research group made important progress in their research on the mechanism of long-chain noncoding RNA regulating myocardial infarction. Their research results were reported in “LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription,” which was published in Nature Communications (Impact factor: 12.12)...
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The results of research by our Institute were published in the European Heart Journal
Recently, the results of our research on the regulation of cardiomyocyte hypertrophy signaling pathways were published in the European Heart Journal. Myocardial hypertrophy is the general term for the increase in the volume of myocardial cells at the cellular level and the thickening of myocardial tissue at the tissue level. It is a disease in which the volume of the heart increases due to the ...
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Nature Communications: E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1
On July 17, 2015, the Center for Developmental Cardiology published “E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1” in Nature Communications. Mitochondrial fragmentation plays an important role in the progression of cardiac diseases, such as myocardial infarction and heart failure. Mitochondria are the major ATP and reactive oxygen s...
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The results of research at our Institute were published in Circulation Research.
Recently, our Institute published the latest research results on the regulation of cardiomyocyte necrosis signaling pathways in Circulation Research. Cardiomyocyte death is the cytological basis of many cardiovascular diseases. Cell death includes apoptosis and necrosis. In the past, it was believed that apoptosis was regulated by signal pathways, while necrosis was not regulated by signal path...
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Our research results were published in Molecular Cell and Nature Communications.
Recently, our Institute’s research results in the field of noncoding RNA and oxidative modification were published in Molecular Cell and Nature Communications. Excessive reactive oxygen species (ROS) can oxidize and modify biological macromolecules to make them function abnormally, thereby causing cell damage. Oxidative modification is related to cancer, aging, neurodegenerative diseases, and ...